With 50% of women suffering at least one UTI over the course of their lifetime, there’s increasing interest in the potential benefits of probiotics for this complaint. Are they effective? Read on to find out how best to care for this aspect of intimate health.
Cystitis is inflammation of the bladder which is usually caused by a bacterial infection. The most common culprits are Escherichia Coli which are naturally present in the digestive system, particularly in the colon and rectum.
Cystitis thus develops when these naturally-present E. Coli bacteria migrate from the colon and rectum to the genitals, travelling up the urethra and becoming implanted in the bladder wall. There they colonise the bladder, and the result is a UTI (1).
UTIs produce a range of particularly troublesome symptoms (2):
Though not usually serious, UTIs can lead to complications, particularly in the kidneys, when the pathogenic bacteria travel along the ureter and colonise the kidneys: it is then referred to as pyelonephritis.
Women have a shorter urethra than men, providing an easier route to the bladder for harmful bacteria.
In addition, the proximity of the anus to the vagina encourages colonisation by bacteria. They migrate to and contaminate the urethra via the hydrolipidic film situated between the anus and vagina.
And during pregnancy and the menopause, the hormonal changes experienced by women can promote urinary stasis (and thus incomplete emptying of the bladder), which itself encourages the growth of pathogenic bacteria in the bladder (these being normally eliminated in urine) (3-4).
Last but not least, during sexual intercourse, the urethral opening is particularly exposed to pathogens and may become contaminated, thus promoting the development of a UTI.
As UTIs are usually caused by infection with E. Coli bacteria, the only treatments health authorities recommend are antibiotics, often single-dose, which eliminates the cystitis symptoms within a few days (5).
They also recommend adequate hydration: drinking plenty of fluid means frequent urination, which enables the pathogenic bacteria to be eliminated from the bladder.
With this in mind, some doctors may recommend taking diuretic plants to increase urine volume (dandelion, field horsetail, burdock, etc.).
Cranberries are small sour berries, often used in North American cooking, which grow in boggy areas and which have become increasingly popular in recent years. Rich in antioxidants and vitamin C, they are considered by many to be a super-food.
But cranberries are primarily reputed to prevent cystitis, due to their high content of proanthocyanidins. These polyphenols are thought to stop E.Coli from adhering to the bladder wall, though this explanation has yet to be confirmed by the EFSA (6).
In addition, the WHO recognizes the traditional use of certain other plants for relieving or preventing UTIs: echinacea and aniseed in particular, because of their immunostimulant and antibacterial properties. There are also other natural remedies for cystitis and excellent natural products for urinary tract health in general (such as the synergistic formulation Complete Uricare).
So what’s the thinking on probiotics for fighting UTIs?
Firstly, some studies point to the existence of urinary flora (7) (and thus a microbiota in the bladder). The existence of a vaginal microbiota (also called vaginal flora) has already been proven.
Certain strains of lactobacillus have shown encouraging results in preventing UTIs, especially Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14, whether administered orally or vaginally (8). A strain belonging to this first species is actually part of the synergistic formulation Vaginal Health, targeted at balancing the vaginal flora.
Several studies investigating the strain Lactobacillus crispatus have also shown an association with a reduction in recurrent UTIs in peri-menopausal women when administered by vaginal suppository (9-10).
However, further research is needed to provide a clear picture of the effects of probiotics on the bladder. But there’s actually another important reason why probiotics should be used in the case of a UTI …
Those who are prone to cystitis will usually suffer several episodes a year, and may therefore receive several antibiotic treatments. Yet we know that antibiotics can significantly damage the intestinal microbiota (11).
In this context, probiotics help to maintain a normal intestinal microbiota during, and especially after, antibiotic treatment prescribed for cystitis (12); in such cases, it’s worth considering the probiotics Probio Forte or Full Spectrum Probiotic Formula (which also includes microorganisms from the species Lactobacillus crispatus).
Curative treatments aside, you can act to help prevent a UTI, by taking measures concerned with vaginal and vulval health.
Since the vaginal flora is composed of, amongst others, Lactobacillus rhamnosus, Lactobacillus salivarus, Lactobacillus casei, Lactobacillus acidophilus and Bifidobacterium lactis, many women keen to take optimal care of their vaginal microbiota regularly take probiotic formulations that include these microorganisms (such as Vaginal Health) (13).
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